34 In August 2013, the FDA alerted consumers of rare but serious and potentially fatal skin reactions, such as Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and acute generalized exanthematous pustulosis (AGEP), linked to acetaminophen use
However, the repeated failure of A-targeted therapies in clinical trials highlights the limitations of focusing on a single pathological mechanism
Nobile CJ, Johnson AD (2015) Candida albicans biofilms and human disease
Deng L, He S, Guo N, Tian W, Zhang W, Luo L
10.1523/JNEUROSCI.6409-11.2012 136
Scientific Communications: prognosis & outcomes 03.00 - RECOVERY, REHABILITATION AND OUTCOME - 03.03 - PROGNOSIS AND OUTCOME AFTER STROKE O - ESOC25-922 EARLY VASCULAR AGING AMBULATORY SCORE IN ACUTE ISCHEMIC STROKE Nikolaos Kakaletsis 1 , Vasileios Kotsis 2 , Naohisa Hosomi 3 , Patrik Michel 4 , Davide Strambo 4 , Youngseo Kim 5 , Konstantinos Vemmos 6 , Maurizio Acampa 7 , Jukka Putaala 8 , Matthias Hermann 9 , Philip Bath, Athanase Protogerou 10 , Charalampos Milionis 11 , George Ntaios 1 , Christos Savopoulos 1 1 First Propedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, AHEPA University Hospital, Thessaloniki, Greece, 2 Third Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, Papageorgiou Hospital, Thessaloniki, Greece, 3 Department of Clinical Neuroscience and Therapeutics, Hiroshima University Graduate School of Biomedical Sciences, Hiroshima, Japan, 4 Stroke Center and Neurology Service, Department of Clinical Neurosciences, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland, 5 Department of Neurology, College of Medicine, Hanyang University, Seoul, South Korea, 6 Department of Clinical Therapeutics of Alexandra Hospital, National and Kapodistrian University of Athens, Athens, Greece, 7 Stroke Unit, Department of Medical Sciences, Surgery and Neurosciences, Santa Maria Alle Scotte General Hospital, University of Siena, Siena, Italy, 8 Department of Neurology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland, 9 University Heart Center Zurich, Department of Cardiology, University Hospital Zurich, Zurich, Switzerland, 10 Cardiovascular Prevention & Research Unit, Clinic & Laboratory of Pathophysiology, Department of Medicine, School of Health Sciences, National and Kapodistrian University of Athens, Athens, Greece, 11 Department of Internal Medicine, Medical School, University of Ioannina, University Hospital of Ioannina, Ioannina, Greece Background and Aims: Understanding the impact of early vascular aging (EVA) on acute ischemic stroke (AIS) outcomes may provide new insights for improving prognostic assessments and developing targeted therapeutic strategies
