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Since ferroptosis is defined by impaired GPX4 activitya critical enzyme in reducing lipid peroxidesGPX4 deficiency triggers acute renal failure by promoting tubular cell ferroptosis [49]

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Some improvements were noted in specific symptoms for female participants, particularly in reducing thirst and fatigue, but these effects were not significant across the broader participant group

& Zhou, J

Jin SM, Lazarou M, Wang C, Kane LA, Narendra DP, Youle RJ

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