A GLP-1 blocker acts by inhibiting the GLP-1 receptor, which modulates the downstream inflammatory pathways linked to: cytokine production immune system activation oxidative stress inflammatory signaling in tissues such as the liver, fat cells, and gut In low doses, blocking GLP-1 receptors appears to influence the immune system without significantly interfering with glucose control which is why this approach is being studied specifically for inflammation rather than metabolic disease
It plays a crucial role in supporting a healthy immune system by enhancing the function of immune cells
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Touti, F., Lautrette, G., Johnson, K.D., Delaney, J.C., Wollacott, A., Tissire, H., et al., ChemBioChem , 2018, vol
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