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Snuff was very expensive and became part of the social ritual at the Qing Dynasty's imperial court as noblemen came to sample this new wonder which was believed to have medicinal properties
Estimating CI from crude numbers If an adjusted RR lacked a CI or p-value but the corresponding 2 2 table was available, the CI was estimated assuming that the ratio UCL/LCL was the same as for the equivalent unadjusted RR
Starting at around 50/50 and adjusting as needed is still the best approach, though
PMID 32451600
There is also a risk of lung disease, such as asthma or other respiratory conditions, and rare cases of popcorn lung have been linked to certain chemicals in vaping liquids, though these are now banned in many regions and no cases are linked to vaping
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