Psychiatry Res 309:114429
This form is standard across the copper-peptide research field, since lyophilization preserves the peptides structural stability during storage and transport in a way that liquid formulations generally cannot match
Considering the fact that the activity of recombinant GPx3 from mammalian cells was similar to that of partially purified human plasma GPx3 18 , the significant drop in activity should be related to the absence of the post-translational modification
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For a contrasting case in which a peptide with a defined endogenous role and a more constrained but still incomplete mechanistic literature has nonetheless attracted sustained research interest, see the epitalon research brief