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These dynamic interactions help ensure that NO is available when needed, particularly in response to conditions like hypoxia and exercise, where vasodilation and increased tissue oxygen delivery are critical (Kim-Shapiro et al., 2005

One of the key roles of SCFAs, particularly butyrate, is to maintain the integrity of the gut barrier by regulating mucin gene transcription in the goblet cells, which increases the mucus layer[39]

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Since GSSG is not readily exported out of mitochondria (Yin et al., 2012), the activity of GR is an important mechanism to control the level of GSSG in mitochondria

58 : 1239 - 1247 Bruns H, Watanpour I, Gebhard MM, Flechtenmacher C, Galli U, Schulze-Bergkamen H, Zorn M, Buchler MW, Schemmer P

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