Increasing research has been focused on the impact of dyslipidemia on female reproduction
& Weiss, M
This review summarises the fundamental features of ferroptosis, discusses the role of VSMC ferroptosis in various vascular diseases, and highlights the emerging anti-ferroptosis therapeutic strategies, which may represent future research trends and focal points in this field
PMID: 8 KhoslaSCauleyJACompstonJKielDPRosenCSaagKGet al
Glymphatic Stasis TBI disrupts the polarization of Aquaporin-4 (AQP4) channels, leading to "glymphatic stasis." The brain cannot clear its own waste, leading to the accumulation of toxic proteins (Tau, Amyloid) [7]
Although pharmacological compounds aimed at inducing ferroptosis, such as erastin and RSL3, or inhibiting it, such as ferrostatin-1 (fer-1), have demonstrated potential in preclinical studies, their application in clinical settings faces challenges, including off-target effects and limited tissue specificity [2,3,4,5,6]
