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Anticoagulants like heparin, warfarin, and newer direct oral anticoagulants (DOACs) present the most obvious interaction question

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Native rhIGF-1 (mecasermin, brand name Increlex) is FDA-approved only for the long-term treatment of growth failure in pediatric patients with severe primary IGF-1 deficiency or with GH gene deletion who have developed neutralizing antibodies to GH