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Curcumin-induced upregulation of SIRT1 has been associated with beneficial effects on various diseases, including cardiac fibrosis, diabetes, and ischemia/reperfusion injury [141,142]

A few forms are chemical in origin

Researchers use in-vitro models of pulmonary fibrosis to study this process, often by treating lung fibroblast cell lines (e.g., MRC-5) with the pro-fibrotic cytokine TGF-1

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GHK is known to work as an anti-inflammatory and antioxidant agent by decreasing inflammatory cytokines and reducing reactive oxygen species (ROS) levels [7]

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