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Patients considering lipotropic injections should be counselled that these products are not substitutes for evidence-based weight management strategies and may represent unnecessary expense without proven benefit

Therefore, there is a need to develop new therapies, such as triple reuptake inhibitors (TRIs), that can block the reuptake of serotonin, norepinephrine, and dopamine

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STAT3 inhibition of gluconeogenesis is downregulated by SirT1