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AGF347-Glu5 inhibits SHMT2 more than 19-fold more potently than AGF347 [167]

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A phase III trial of oral octreotide capsules demonstrated that this treatment can safely sustain suppressed levels of GH and IGF-1 and reduce the severity of symptoms in patients with acromegaly previously controlled by injectable SRL therapy, with the added benefit of no injection-site reactions

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