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This finding is particularly noteworthy given that some trials extended to 24 weeks of continuous exposure and included participants with obesity-related comorbidities who might be expected to have higher baseline health risks

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Hydroxocobalamin, which the body retains longer than cyanocobalamin, often allows less frequent dosing once levels stabilize

MOTS-c has little human safety data of any kind

Those with pre-existing cardiac conditions or on medications affecting potassium levels may require closer monitoring

In this article, well break down why vitamin B12 matters, how injections work, and what the ideal dosage and frequency might look like for you