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3 EPIDEMIOLOGY The exact prevalence of BO in the general population of the USA is unknown as it is present in both symptomatic and asymptomatic patients

Honda K, Littman DR (2016) The microbiota in adaptive immune homeostasis and disease

Evaluates new medical technologies: NICE assesses the clinical and cost-effectiveness of new medical technologies, such as drugs and medical devices, to determine whether they should be made available on the NHS

Wipe the stopper with an alcohol swab before every draw

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Apply gentle pressure with a clean alcohol pad if any bleeding occurs (typically minimal to none)