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and 3) a saturation of the transsulfuration pathway related to a dietary excess in methionine in cases of adequate folate and cobalamin intake

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When used for the routine nursing care of patients with tracheostomy, 1 to 2 mL of a 10% to 20% solution may be given every 1 to 4 hours by instillation into the tracheostomy

PMID: 26 DurringtonHJGioan-TavernierGOMaidstoneRJKrakowiakKLoudonASIBlaikleyJFet al

That's not a bad way to get to 10g, but double-dosing will likely result in more clouding and a more intense taste

Furthermore, both k p2 and k O2 register as the two most sensitive parameters with respect to the main effects, with k p4 also sensitive