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(More information) Mounting evidence from preclinical studies shows that curcumin modulates numerous molecular targets and exerts antioxidant, anti-inflammatory, anticancer, and neuroprotective activities

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The specificity of these responses relies on the spatial and temporal control of ROS production, which distinguishes transient signaling events from sustained oxidative stress

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A basic environment or the proximity of a metal cation are key determinants for the tendency of thiol groups to become deprotonated and consequently be affected by oxidation and spontaneous S -glutathionylation [222,223,224,225,226,227]

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