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For instance, elevated NT-proBNP may prioritize the use of SGLT2 inhibitors or tirzepatide for patients with cardiac stress, while high hsCRP or Pro-C3 may point to liver inflammation and fibrosis, guiding the use of GLP-1RAs or dual agonists (172)

To get a better management of RA, a personalized combination of these drugs is recommended

Synergy: Can They Be Used Together

Studies have found that amino acids such as arginine, leucine, glutamine, and methionine not only serve as essential nutrients for cell survival but also regulate autophagy by modulating mTORC1, GCN2, and AMPK signaling [61, 62]