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Moreover, intracellular levels of glucose-6-phosphate (G6P) were not reduced following melatonin treatment ( Figure 5H ), whereas fructose-6-phosphate (F6P) was markedly decreased ( Figure 5I )

Thus, glutathionylation of Cys390 and contact between the GSH group and the binding partners of TRAF6 is in accordance with the current structural knowledge

Relevance of molecular docking studies in drug designing

Kan T, Li H, Hou L, Cui J, Wang Y, Sun L, et al

The signal is transmitted to special neurons in the brain through the brain-gut axis and stimulates the secretion of endogenous reward substances

"Mechanistic studies on a novel, highly potent gold-phosphole inhibitor of human glutathione reductase"