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IMPORTANT SAFETY INFORMATION CONTRAINDICATIONS This product should not be used in patients who have severe allergies, marked by a history of anaphylaxis or history or presence of multiple severe allergies, and should not be used in patients with a history of allergies to Gram-positive bacterial proteins or lidocaine contained in this product

Clinical overview and patient information

A: Ampoules should be kept in a cool, dry environment below 25C

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These improvements are typically more pronounced when the injections are part of a comprehensive program including healthy nutrition and physical activity

FOXO4-DRI can selectively and potently target senescent cells for p53-dependent apoptosis Given the reported pro-apoptotic role of active p53 when recruited to mitochondria, we next assessed the effects on senescent cell viability