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When the tumours reached a volume of approximately 50 mm 3 , mice were randomized into two treatment groups: vehicle and palbociclib (100 mg kg 1 five times per week)

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Under conditions in which the GPx activity is rate limiting, the rate of decrease in the A340 is directly proportional to the GPx activity in the sample (35)

These investigations remain confined strictly to laboratory research contexts and do not represent approved therapeutic use

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