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Empirical data regarding reliability or validity qualified four of the five smoking cessation measures (duration of abstinence, quit attempts, rate of abstinence/quitting, change in smoking quantity/frequency) as acceptable

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Major hallmarks often observed in early AMD are thickening of the Bruchs membrane, reduced choroidal blood flow, and the appearance of drusen, deposits of metabolic products accumulating between the RPE and Bruchs membrane [6, 8,9,10]

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