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This occurs relatively quickly in comparison to the re-synthesis of the neuron-characteristic metabolite N-acetyl aspartate (NAA), considered to be an indicator of neural health and fitness (Demougeot et al

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Neoadjuvant Approaches to Advanced Thoracic Malignancies

[DOI] [PMC free article] [PubMed] [Google Scholar] 445.Dobrian A.D., Galkina E.V., Ma Q., Hatcher M., Aye S.M., Butcher M.J., Ma K., Haynes B.A., Kaplan M.H., Nadler J.L

In addition, the sample size of first-in-human studies is generally small, enabling the observation only of effects that occur very often