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Increased ROS concentrations in PTSD have detrimental effects on calcium homeostasis, resulting in mitochondrial enlargement and leakage of Ca 2+ ions, thereby creating a vicious cycle in which ROS enhance cytosolic Ca 2+ levels, and Ca 2+ enhances ROS production, which may worsen PTSD symptoms

Ivanov I, Saam J, Kuhn H, Holzhtter H-G (2005) Dual role of oxygen during lipoxygenase reactions

Next, cells were washed with PBS, incubated for a further 6 to 12 h, lysed, and bacterial enumeration was conducted to assess the internalization capabilities