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Numerous studies have confirmed the close relationship between hyperhomocysteinemia (HHcy) and the occurrence/development of various diseases such as cardiovascular diseases, neurological disorders, thrombotic diseases, and tumors

Interestingly, TNF-alpha has been shown to interrupt tight junctions, thus worsening any underlying tight junction dysfunction

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It's a really, really good thing for a lot of people, not necessarily good for everybody, but it's absolutely an amazing thing for a lot of people