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Once the tumor volume reached approximately 100 mm 3 , twelve mice were assigned at random (n = 3) and received the same treatment as previously described

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Opioids have been used for thousands of years and they originate from the milky fluid (called latex) of the poppy plant

[1] This means it has not undergone the rigorous testing required for pharmaceutical products, and its quality, purity, and potency may vary considerably between manufacturers

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JAMA 2021;325(18):18311832