Emerging evidence implicates programmed necrosis (necroptosis), pyroptosis (gasdermin-D pore formation) and ferroptosis (lipid peroxidation driven by iron accumulation) as additional contributors, implying multiple, drug-specific death executors [72, 79, 84,85,86]
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Intriguingly, the degree of improvement in cortical perfusion and renal blood flow (RBF) in the kidney that underwent intra-arterial renal artery injection of MSCs was comparable to that of the contralateral kidney
