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In most human cancer cells, the expression of DKK3 (Dickkopf-related protein 3) is epigenetically silenced by methylation of CpG islands in promoters (Nozaki et al., 2001)

Cells can either synthesize serine from glycolysis-derived 3-phosphoglyceric acid (3PG) or acquire it from external sources [87]

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PER1 interaction with GPX1 regulates metabolic homeostasis under oxidative stress