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Figure 8: Changes in phospho-Akt immunoreactive cell count between the control group and two experimental treatment groups

A prospective cohort study reported that combining sTfR and ferritin into a ratio-based index achieved an area under the curve (AUC) of 0.87 in predicting A-positivity, outperforming traditional individual biomarkers (Du et al., 2024)

J Med Chem DOI:10.1021/acs.jmedchem.7b00389 [3]

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Endogenous stimuli strategies make use of biochemical differences within the TME, including extracellular and intracellular pH gradients, altered redox status, overexpression of proteases and hypoxic conditions [46, 47, 49]