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Effects depend on peptide class, dose, delivery route, and baseline health

Journal of Controlled Release 161 , 505522, (2012)

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Fatty acid + ATP + CoA Acyl-CoA + PP i + AMP Table of the Mammalian Acyl-CoA Synthetase Family Fatty Acid Deactivation Once a fatty acid is esterified to coenzyme A forming an acyl-CoA, its fate is not destined for oxidation in the mitochondria or the peroxisomes

Nasal delivery may offer extra perks for gut research since it avoids first-pass metabolism