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Critics have questioned its accuracy and reproducibility, expressing concerns that excessive reliance on algorithms might lead to a narrow or oversimplified understanding of the complexity inherent in Chinese medicine [673, 674]

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In recent years, Nuclear Magnetic Resonance (NMR) spectroscopy has been widely used for quantitative metabolite analysis, enabling a comprehensive and unbiased profiling of small molecules in biofluids and tissues 17,18,19,20

Some individuals report noticeable changes within days (often in comfort and inflammation perception), but the more meaningful improvements related to tissue remodeling, rehab tolerance, and return to function commonly take weeks

10.1016/j.ejphar.2021.174660 93 LiX.HuangW.TanR.XuC.ChenX.LiS.et al (2023a)