In addition, specific mitochondrial proteins in NDEVs, such as subunit 6 of respiratory chain complex I, subunit 10 of complex III, and the neuroprotective proteins Humanin and MOTS-c, were significantly reduced in PACS patients with neuropsychiatric symptoms, but not in those without these symptoms, relative to controls
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However, Huberman is still on the fence about the long-term use of rapamycin, particularly due to its immune-suppressing properties at higher doses
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