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The dual MEK/FLT3 inhibitor E6201 exerts cytotoxic activity against acute myeloid leukemia cells harboring resistance-conferring FLT3 mutations
: - - , - , - - - : 4,5 (1 ) , 150 - 200
Experimental and therapeutic
Studies in AD and preclinical AD have shown that some medium- or long-chain acylcarnitines involved in fatty acid transportation and metabolism were associated with cognitive decline (Fiandaca et al., 2015
The current study showed that LCn improved sperm quality, which was in line with earlier research on LC showing that LC regulates Sertoli cell functions and significantly boosts the release of pyruvate and lactate, which are necessary for energy production and sperm cell development in the testis.[] The improvement of sperm quality by LCn in this part of the experiment is consistent with the antioxidant action of LCn and its beneficial effect on sex hormones demonstrated in this study
