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IGF-1 also plays a key role in maintaining epidermal homeostasis, helping to prevent skin aging and maintain a youthful appearance (Tavakkol et al., 1999)

While adaptive Th2 cells have long been implicated in asthma pathogenesis, group 2 innate lymphoid cells (ILC2s) are now recognized as critical initiators and amplifiers of allergic airway inflammation

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This study thus identifies Kyn accumulation as a potential contributor to mTOR activation and metabolic target of the therapeutic action by NAC in patients with SLE