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3 Hepatocyte necrosis: apoptosis-inducing factor (AIF) and endonuclease G, along with other mitochondrial components, are released into the cytoplasm, causing chromatin condensation and DNA fragmentation

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In pathological context, ectopic lipid accumulation and consequently lipotoxicity occurred when FAO was defective in cardiomyocyte, serving as a mechanistic link between AF/obesity and metabolic disorder (Haffar et al., 2015

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Antidepressant treatment with Fluoxetine during pregnancy and lactation modulates the gut Microbiome and metabolome in a rat model relevant to depression