This HO-CO pathway has been recently proposed to be involved in the defence against oxidative stress and the deleterious effects of NO, since it removes the cytotoxic free heme, and produces some molecules with antioxidant and anti-inflammatory effects, such as biliverdin and CO [8, 3840]
J Endocrinol Invest (2015) 38:28394
NMDA receptors are sensitive to glutamate binding, the major excitatory neurotransmitter in the brain whose extracellular levels increase abnormally during insults, such as ischemia
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For a product page, we describe it more carefully as supporting the appearance of a clearer, more radiant and more even-looking complexion, rather than claiming it treats pigmentation
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