Preserves natural feedback loops: The physiological stimulation allows for endogenous regulation without suppressing the pituitary axis
Temel JS, Abernethy AP, Currow DC, Friend J, Duus EM, Yan Y, Fearon KC
Cdigo 010515
Dysregulated iron metabolism is a key pathogenic feature of LN (213), and emerging evidence links these disturbances to ferroptosis (214)an iron-dependent cell death driven by lipid peroxidation, distinct from apoptosis/necrosis ( 3.5.1 CD4 T-cell iron dyshomeostasis drives SLE/LN Iron overload promotes pathogenic T-cell differentiation and accelerates disease in lupus-prone models (215): 1) In MRL/MpJ-Fas (lpr)/J (MRL/lpr) mice, iron overload expands T follicular helper (Tfh) cells, germinal center (GC) B cells, and pro-inflammatory cytokine-secreting CD4 T cells
PubMed Central, Huang, Xiao, et al
\Wound Healing & Tissue Repair: 2 faster epithelial barrier restoration