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The active site is located in a cleft situated between domains I and II and each subunit binds two molecules of a competitive inhibitor S-hexylglutathione
doi: 10.1136/bmjopen-2023-081280
PubMed PMID: 9616382
In Alzheimers disease models, spine loss in the hippocampus is one of the earliest and most consistent pathological findings
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