Russian NAFLD guidelines recommend EPL 1800 mg/day (2 300 mg capsules, three times a day) for 1224 weeks as supportive treatment for patients with NAFLD [16]
In fact, the peptide has actually been shown to prevent severe side effects associated with medications for diabetes and psychiatric conditions, including catalepsy, somatosensory disturbance, and QTc prolongation in the heartwhich can lead to fatal arrythmia [13, 14]
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Here, Ekihiro Seki & team implicate the fungal sensing adaptor protein CARD9 in maintaining gut barrier integrity under metabolic stress, finding that the loss of fungal sensing exacerbates liver injury in a murine model of MASLD