Clinical trials are necessary to determine the appropriate dosage for humans
declares having received consulting honoraria from Amgen, Boehringer Ingelheim, Merck, Pfizer, Aegerion, Novartis, Sanofi, Takeda, Novo Nordisk and Bayer, and research grants from British Heart Foundation, MRC (UK), NIHR, PHE, MSD, Pfizer, Aegerion, Colgate and Roche
Hydroxocobalamin is a long-acting, highly bioavailable form of B12, making it a preferred choice for both clinical use and B12 deficiency correction
We consider the cause of the deficiency, how well they absorb it, and what they prefer
For most of the population, though, one capsule is more than enough to meet vitamin B12 requirements if someone is not consuming enough B12 through their diet
Ann Hepatol