In several meta-analyses, UPT was found to be the most effective small molecule drug for inducing clinical remission and clinical response, but it had the highest incidence of adverse events in patients with moderate to severe UC [12, 179]
Importantly, oxidative stress and glutathione deficits have also been implicated in depression, bipolar disorder, and schizophreniabroadening their potential impact across mental health care
G.SchapiraA
"Vitamin B 12 "
The latter is important as it allows the serial imaging of these lesions in vivo by MRI, revealing that many slowly expand over time (Dal-Bianco et al., 2017

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