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Examples of otoprotectants include, but are not limited to, PNU 37883, AM 92016, XE-991, linopirdine, Ro 04-5595, ()-1-(1,2-diphenylethyl)piperidine, ifenprodil, SYM 2206, FPL 64176, ZK 93423, m-chlorophenylbiguanide, 2-APB, MR 16728, d-tubocurarine, berbamine, E6 berbamine, hernandezine, and isotetrandrine

& Dore, S

Diabetes was confirmed by measuring 3 consecutive days of elevated blood sugar

Alsaud et al

139,140 Adiponectin activates the AMPK and PPAR- signaling pathways through adiponectin receptor 1 (AdipoR1) and AdipoR2 respectively, leading to enhanced fatty acid oxidation and glucose uptake in muscle, along with suppressed gluconeogenesis in liver tissues

Adjusting Protocols Based on Response Individual response variation means standard protocols serve as starting points rather than fixed prescriptions