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doi: 10.1002/ptr.6334

doi: 10.1016/0196-9781(87)90163-x

Subsequent research expanded the concept of glutathione peroxidase from a single enzyme to a multifunctional family with diverse physiological roles across tissues and organisms

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In the context of protein oxidation, the relationship between AGEs and the generation of AOPPs is noteworthy (Figure 2) ( AGEs are produced in a slow and controlled process, accumulating in the body, including the skin ( 3.2.3 Protein carbonylation In addition to AOPPs and AGEs, protein carbonylation (PC) serves as another marker of protein oxidation in patients with AD