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Camelid single-domain antibodies, often also referred to as nanobodies, offer a promising alternative to conventional IgGs

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70 Additionally, lactylation at K91 of transcription factor EB (TFEB) impedes it from interacting with E3 ubiquitin ligase WW domain-containing E3 ubiquitin protein ligase 2 (WWP2), thereby inhibiting TFEB ubiquitination and proteasome degradation and eventually augmenting TFEB activity

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