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Pros: Zero visible breast scarring Appealing to patients with scar concerns Cons: Only compatible with saline implants (silicone implants cannot be passed through this route unfilled) Least direct surgical access of all techniques Lower precision for implant positioning Not widely offered

Biochemical tests for AGHD diagnosis are imperfect, and their accuracy is strongly affected by the pre-test probability of the condition

This effect was limited to pro-IL-1 regulation, as LDH release, which is a marker of pyroptosis, remained unchanged

Conversely, hepatic enzymes may be inhibited and bioavailability increased (e.g

10.1016/j.cell.2016.09.031 95 GoberdhanD

J Clin Invest 121:37563762