As an enzymatic cofactor in the synthesis of monoamine neurotransmitters, including serotonin and dopamine, reduced BH4 levels contribute to decreased 5-Hydroxytryptamine (5-HT) and dopamine (DA) levels, which induces depressive-like behaviors (Nasser et al., 2014
PubMed Kovalzon VM, Tsibulsky VL
Dose: Dosage varies depending on your specific needs however, anything between 300-1000mg a day for women and 200mg a day for men may be recommended
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Age, Medications, and Underlying Conditions Glutathione naturally declines as we age
Histopathological changes in cerebellar neuronal structure, such as loss of Purkinje cells (PCs), have been discovered in the postmortem brains of many ASD patients
