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Of the total adverse events reported, 37% were gastrointestinal in nature [207 events in 73 (77%) of 95 participants], most frequently nausea [67 events in 53 (56%) participants], vomiting [43 events in 23 (24%) participants], and dyspepsia [32 events in 27 (28%) participants]

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Beta-3-AR knockout mice were completely unresponsive to chronic lipolytic effects, demonstrating that this receptor pathway is essential for sustained fat-reducing activity

Neural Regeneration Research, 2022, 17 3: 482-487

Gene chip assay Total RNA was extracted from control and BPC-157-treated cells exposed for 12 hours using an RNeasy Mini Kit (Qiagen, Valencia, CA, USA)