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Experimental receptor binding assays indicate that Cagrilintide can activate both amylin receptor subtypes and the calcitonin receptor itself, producing measurable signaling responses in cellular assay systems

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Watson REB, Ogden S, Cotterell LF, Bowden JJ, Bastrilles JY, Long SP, Griffiths CEM

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Furthermore, the previously observed upregulation of PDGFB, EGFR, FGF2, and FGFR1 expression in BPC157 cells was abolished upon BACH1 knockdown (Fig

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