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Molecular Composition and Mechanistic Profile BPC-157 (Body Protection Compound-157): A synthetic pentadecapeptide (sequence Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val

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doi: 10.1016/j.immuni.2013.08.013 252 AdlercreutzHPulkkinenMOHamalainenEKKorpelaJT

Everything needs to be in balance.[ref][ref] Prostate cancer risk is increased with 4-HOE1(E2) metabolites also.[ref] In general, the estrogen metabolites that start with 2 are good, and the ones that start with 4 or 16 need to be limited or at least eliminated quickly from the body.[ref] Here is a diagram of how these metabolites go together: As you can see, upregulating the CYP1A1 enzyme is going to increase the 2-OHE1 path

Gmez-Garzn M, Gutirrez-Castaeda LD, Gil C, Escobar CH, Rozo AP, Gonzlez ME, Sierra EV