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3, Oncogenic PI3K/AKT signaling stabilizes and activates nuclear factor erythroid 2related factor 2 (NRF2), a key regulator of antioxidant genes, driving upregulation of GSH biosynthetic enzymes

Calder, P

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These changes are accompanied by significant deficiencies in antioxidant enzymes compared to healthy subjects

In human studies, alpha-MSH applied topically in a cream reduced nickel-induced contact eczema

Some research has found that people with obesity had lower levels of vitamin B-12, but further studies are needed to confirm a link between weight and B12 levels