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established a chemical cocktail of CHIR, A8301, and SAG (a Hedgehog signaling activator) combined with EGF, HGF and BMP4, which significantly promoted the expansion and stemness maintenance of HPCs (Pan et al., 2019)

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Cellular mechanisms of thyroid hormones and interaction with nuclear receptors Thyroxine (T4) and triiodothyronine (T3) play crucial roles in metabolic processes regulation, growth, and development