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In conclusion, lower CSC concentrations activate the typical P53-dependent apoptotic death signalling pathway resulting in mitochondrial membrane depolarisation

For individuals 20 y and older, age-standardized prevalence of intestinal metaplasia (dark blue) and dysplasia (light blue) are shown in this graph

By this estimate, the 2000 puffs from a Breeze Pro equate to about 6-10 packs of cigarettes in terms of the number of inhales, but because nicotine concentrations vary, the comparison isnt direct

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